CYP2C9 Index Natura structuraque biochemica | Genetica | Pharmaca ad CYP2C9 relata | Notae | Nexus externi | Tabula navigationis"Structure and dynamics of the membrane-bound cytochrome P450 2C9""Membrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active site"

Cytochromata P450


-atis, n.Numerus ECcytochromatum P450polypeptidumacidis aminicisgenichromosomate 10







Esculaap4.svg


Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt.





Cytochroma P450 CYP2C9.


Cytochroma P450 CYP2C9 (-atis, n.) (Numerus EC: 1.14.13.48) est haemoproteinum et pars gregis cytochromatum P450.




Index





  • 1 Natura structuraque biochemica


  • 2 Genetica


  • 3 Pharmaca ad CYP2C9 relata


  • 4 Notae


  • 5 Nexus externi




Natura structuraque biochemica |


Cytochroma P450 CYP2C9 est et polypeptidum et haemoproteinum, quod ex 490 acidis aminicis (massa 55.628 Da) constitutum est. Intra cellulam enzymum hoc in ancoris membranae stat[1].



Genetica |


Nomen geni cytochromatis est CYP2C9 locus cuius geneticus in chromosomate 10 humano locatus est (10q23.33).



Pharmaca ad CYP2C9 relata |










Pharmaca relata ad CYP2C9[2][3].

SubstratiInhibitores[4]Inductores[5]

  • Analgetica
    • Celecoxibum

    • Diclofenac


    • Ibuprofenum[6]

    • Naproxenum


  • Antidepressiva
    • Amitriptylinum

    • Fluoxetinum



  • Inhibitor receptorii angiotensini II
    • Candesartanum

    • Irbesartanum

    • Losartanum



  • Sulphonylureae
    • primae generationis
      • Tolbutamidum

    • secundae generationis
      • Glipizidum

      • Glibenclamidum

      • Glimepiridum

      • Glyburidum



  • Tamoxifenum

  • Fluvastatinum

  • Ketaminum

  • Torasemidum

  • Cannabis



  • Fluconazolum (forte)


  • Acidum valproicum (forte)

  • Amiodaronum

  • Antidepressiva
    • Sertralinum


  • Statini
    • Fluvastatinum

    • Lovastatinum




  • Rifampicinum (forte)


  • Secobarbitalum (forte)

  • Phenobarbitalum


Notae |



  1. ↑ Cojocaru V, Balali-Mood K, Sansom MS, Wade RC (2011). "Structure and dynamics of the membrane-bound cytochrome P450 2C9". PLoS Comput Biol 7 (8): e1002152 


  2. ↑ Cozza KL, Armstrong SC (2001). The Cytochrome P450 System. Drug Interaction Principles for Medical Practice. Washington, DC: American Psychiatric Publishing


  3. ↑ Preskorn SH (1996). Clinical Pharmacology of Selective Serotonin Reuptake Inhibitors. 1st ed.: Professional Communications, Inc.


  4. ↑ Inhibitor cum subtratorum effectibus fortioribus


  5. ↑ Inductor cum subtratorum effectibus minoribus


  6. ↑ Berka K, Hendrychová T, Anzenbacher P, Otyepka M (2011). "Membrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active site". J Phys Chem A 115 (41): 11248-55 



Nexus externi |


  • Descriptio genetica CYP2C9: https://ghr.nlm.nih.gov/gene/CYP2C9#

-

Popular posts from this blog

Garniga Index Insigne | Geographia | Ethnográphia | Oeconomia | Historia | Clari cives | Urbis administratio | Ecclesia Catholica Romana | Fractiones, vici et loci in municipio | Municipia finitima | Nexus interni Nexus externi | Pinacotheca | Notae | Tabula navigationis° ′ ″ Sept., ° ′ ″ Ort.Pagina interretialisPagina officialisTovazzi Giangrisostomo OFM - NOTITIA ECCLESIARUM TRIDENTINAE CIVITATIS AC DIOECESIS Clerus et Diocesis Tridentina exeunte anno 1826Amplifica

Image
Municipia in provincia TridentiMunicipia Territorii Vallis AthesinaeLoci thermales Tridentini-Athesiae Superioris/Tirolis Meridionalis -ae, f. ItalianeoppidumItaliaemunicipiumRegioneTridentino-Alta Athesia/Tirole MeridionaliProvincia Libera TridentinaTerritorium Vallis Athesinae Garniga Garniga Terme Theodisce: Garnich Administratio Terra: Italia Regio: Tridentinum-Athesia Superior/Tirolis Meridionalis Provincia: Tridentina Comprehensorium: Territorium Vallis Athesinae Indicia fundamentalia Coordinata: ° ′ ″ Sept. , ° ′ ″ Ort. Res aliae Zona temporalis: UTC+1 Nota autocineti: TN Nomen incolarum: Garnigeri Charta Pagina interretialis Garniga [1] [2] [3] (-ae, f. ) (Italiane: Garniga Terme ) est oppidum Italiae et municipium, in Regione Tridentino-Alta Athesia/Tirole Meridionali et in Provincia Libera Tridentina ( Tridentinum ) situm. Incolae Garnigeri appellantur Municipium pertinet ad Territorium Vallis Athesinae. Index 1 ...
Read more

Saint-André (Pyrenaeus Orientalis) Nexus interni Nexus externi | Tabula navigationisOpenStreetMapGeoNames66168De hoc commune apud cassini.ehess.frHuius communis pagina interretialisAmplifica

Image
Communia praefecturae Pyrenaei Orientalis CatalanecommuneFrancicum2012praefecturaePyrenaei OrientalisOccitania et Ruscinone1 Ianuarii2016Occitania Ruscinone Meridiano et Pyrenaeis Saint-André: ecclesia Saint-André: communis tabula Saint-André (Catalane Sant Andreu de Sureda ) est commune Francicum 3'266 incolarum (anno 2012) praefecturae Pyrenaei Orientalis in regione australi Occitania et Ruscinone (a die 1 Ianuarii 2016 Occitania Ruscinone Meridiano et Pyrenaeis). Nexus interni Indicem communium praefecturae Pyrenaei Orientalis Nexus externi | Vicimedia Communia plura habent quae ad Saint-André spectant. Situs geographici et historici: Locus : 42°33′4″N 2°58′24″E  • OpenStreetMap  • GeoNames  • " 66168 " apud INSEE De hoc commune apud cassini.ehess.fr Huius communis pagina interretialis .mw-parser-output .stipulapadding:3px;background:#F7F8FF;border:1px solid grey;margin:auto.mw-parser-output...
Read more

Is there a way to get `mathscr' with lower case letters in pdfLaTeX?mathscr (LaTeX or XeLaTeX)Blackboard bold characterssome greek letters disappear from PDFs included with includegraphicsBeamer 3.30 with helvet - Problem with upper-case Greekpoor man's condensed with pdflatexlower case calligraphic letters in mathdesignHeadings with Trajan fontA calligraphic font with small (lowercase) lettersHow to use mathbbol only for greek and lowercaseA calligraphic font with lowercase letters, using mathscr style and not boldedIs there a way to write slanted non-italic (especially bold/bb lowercase) letters in math mode?

Image
It grows, but water kills it Why Shazam when there is already Superman? Does IPv6 have similar concept of network mask? Why can't the Brexit deadlock in the UK parliament be solved with a plurality vote? Fear of getting stuck on one programming language / technology that is not used in my country Hash table solution to twoSum Strong empirical falsification of quantum mechanics based on vacuum energy density? How do you make your own symbol when Detexify fails? What if you are holding an Iron Flask with a demon inside and walk into Antimagic Field? How can I avoid dust and bubbles when installing window film? This is why we puzzle What (the heck) is a Super Worm Equinox Moon? How do you respond to a colleague from another team when they're wrongly expecting that you'll help them? Electoral considerations aside, what are potential benefits, for the US, of policy changes in the tweet recognizing Israel's Golan annexation? Angel of Condemnation -...
Read more